Miguel Madrid-Mencía
Backend & Cloud Engineer · Genomics & Applied ML
Toulouse, France · miguel.madrid.mencia@gmail.com
10+ years across research, genomics, and cloud engineering. 1 first-author and 6 co-authored peer-reviewed publications with 135+ citations. Contributed to a pending patent in applied bioinformatics and genomic data processing.
Experience
Egen.ai — Senior Backend & Cloud Engineer
Jan 2025 – Aug 2026Hybrid: US, France
Applied ML Systems. US cloud and AI consultancy. Acquired from Qarik Group in Jan 2025 — role and scope were continuous across the acquisition.
- Built a multi-agent AI orchestration system on GCP for a pharma R&D client, applying genomics domain knowledge to shape agent design.
- Developed GCP Agents and A2A orchestration via MCP/ADK.
- Built a Twilio-based testing framework to automatically generate all mood and user behaviour call combinations for a Voice AI system, replacing manual script configuration.
- Hardened CI/CD pipelines, code quality gates, and security standards for a US financial client — reducing production incidents.
Qarik Group — Senior Backend & Cloud Engineer
Feb 2024 – Dec 2024Hybrid: US, France
GCP-focused cloud consultancy. Acquired by Egen.ai in Jan 2025; role and projects were continuous across the acquisition.
- Delivered an API for data ingestion into BigQuery, deployed on GCP with Terraform and Concourse, for a US biotech client.
Illumina, Inc. — Senior Software Engineer
Mar 2022 – Feb 2024Hybrid: UK, France
Cloud genomics platform (Illumina Connected Analytics) and personalized medicine.
- Benchmarked privacy-preserving data-sharing approaches (homomorphic encryption vs. synthetic data) for the Illumina Connected Analytics platform.
- Built ML pipelines for genomics and GWAS on the Illumina Connected Analytics platform.
- Contributed to a pending patent in applied bioinformatics and genomic data processing — built the Hail/Python variant data-processing layer behind the ML model.
Cancer Research Center of Toulouse (CRCT) — Bioinformatics Engineer
Oct 2018 – Feb 2022Toulouse, France
Translational cancer research center (INSERM). Network biology, epigenomics, and cancer multi-omics.
- Built reproducible Snakemake ML pipelines processing multi-omics datasets (RNA-seq, DNA methylation, 3D chromatin) across multiple cancer cohorts.
- 1 first-author and 6 co-authored peer-reviewed publications with 135+ citations in oncology and systems biology.
- Built GARDEN-NET, a web tool for 3D chromatin interaction analysis — published in Nucleic Acids Research.
Spanish National Supercomputing Center (BSC) — Research Engineer
Jul 2017 – May 2018Barcelona, Spain
European HPC center hosting MareNostrum. Life Sciences department.
- Developed a geospatial visualization platform for AQuAS to analyse health outcomes and quality indicators across Catalonia.
- Built the OpenEBench embeddable benchmarking widget (sole author) — a d3.js radial arc widget used by scientific tools across the ELIXIR European benchmarking platform.
- Primary contributor (79 of 110 commits) to the OpenEBench submission infrastructure — Docker sample containers, Nextflow pipeline generator, Vagrant multi-service VM, and SFTP submission service.
Spanish National Cancer Research Center (CNIO) — Research Technician
May 2016 – Jun 2017Madrid, Spain
Spain's national cancer research institute. Structural biology and molecular oncology.
- Developed a reproducible workflow (Structure-PPi v2.0) to identify mutation clusters at protein-protein interfaces, including web-based visualization.
- Built REST API services for the European OpenMinTeD biomedical text-mining platform, wrapping NLP tools as standardized web services.
Education
Master in Master in Bioinformatics and Computational Biology
Sep 2015 – May 2016Instituto de Salud Carlos III
Master's Thesis: Structure-PPi v2.0 — Annotating Cancer-Related Single-Nucleotide Variants at Protein-Protein Interfaces.
Bachelor in Computer Engineering (Information Technologies)
Oct 2011 – Sep 2015Universidad Complutense de Madrid
Bachelor's Thesis: Computer Vision Adapted to Optical Coherence Tomographies.
Certifications
Teaching
Text Mining for Bioinformatics
Apr 2017 – May 2017Guest Lecturer · Instituto de Salud Carlos III
Designed and delivered a 15-hour intensive module on biomedical text mining and NLP for the Master in Bioinformatics and Computational Biology (Madrid).
- Large-scale literature extraction from PubMed and PMC via the NCBI Entrez API (BioPython).
- NLP pipelines in Python/NLTK: tokenization, POS tagging, n-grams, inverted indexing, lemmatization — adapted for bioinformaticians with varied programming backgrounds.