Miguel Madrid-Mencía
Senior Backend & Cloud Engineer | Bioinformatics & AI Systems
Toulouse, France · miguel.madrid.mencia@gmail.com
10+ years building cloud-native systems across genomics, healthcare, and AI. 1 first-author and 6 co-authored peer-reviewed publications with 127+ citations.
Experience
Egen.ai — Senior Backend & Cloud Engineer
Jan 2025 – PresentHybrid: US, France
Applied ML Systems. Technology services through cloud, data, AI, and platforms. (Acquired from Qarik Group Jan 2025 — role and scope were continuous across the acquisition.)
- Architected a multi-agent AI orchestration system on GCP for a pharma R&D client, applying genomics domain knowledge to shape agent design.
- Developed GCP Agents and A2A orchestration via MCP/ADK for pharma and biotech clients.
- Built an automated data pipeline migration tool with an internal developer API for healthcare and precision medicine workloads on GCP.
- Built a Twilio-based testing framework to automatically generate all mood and user behavior call combinations for a Voice AI system, replacing manual script configuration.
- Hardened CI/CD pipelines, code quality gates, and security standards for a US financial client — catching production issues earlier and reducing error-prone contributions across the team.
Qarik Group — Senior Backend & Cloud Engineer
Feb 2024 – Dec 2024Hybrid: US, France
GCP-focused cloud consultancy. Acquired by Egen.ai in Jan 2025; role and projects were continuous across the acquisition.
- Delivered an API for data ingestion into BigQuery, deployed on GCP with Terraform and Concourse, for a US biotech client.
Illumina, Inc. — Senior Software Engineer
Mar 2022 – Feb 2024Hybrid: UK, France
Genetic analysis technologies: personalized medicine, disease research, drug development.
- Evaluated privacy-preserving data sharing solutions to reduce friction from restrictive genomic data policies.
- Built machine learning pipelines on Illumina Connected Analytics (ICA), HPC, and AWS.
- Designed and optimized Snowflake-based data models for genomics and GWAS pipelines.
- Co-authored a pending patent in applied bioinformatics and genomic data processing.
Cancer Research Center of Toulouse (CRCT) — Bioinformatics Engineer
Oct 2018 – Feb 2022Hybrid: Toulouse, France
Translational cancer research center in Toulouse, focused on oncology and systems biology.
- Designed reproducible ML pipelines for multi-omics analysis of pancreatic and lung cancer, scaled across cancer types.
- 1 first-author and 6 co-authored peer-reviewed publications with 127+ citations in oncology and systems biology.
- Built GARDEN-NET, a web tool for 3D chromatin interaction analysis, still in active use — published in Nucleic Acids Research.
Spanish National Supercomputing Center (BSC) — Research Engineer
Jul 2017 – May 2018Barcelona, Spain
European HPC center hosting the MareNostrum supercomputer.
- Developed a platform for AQuAS to analyze health outcomes and quality indicators through an interactive geospatial map.
- Built the OpenEBench embeddable benchmarking widget (sole author) — a d3.js radial arc widget used by scientific tools across the ELIXIR European benchmarking platform.
- Primary contributor (79 of 110 commits) to the OpenEBench submission infrastructure — Docker sample containers, Nextflow pipeline generator, Vagrant multi-service VM, and SFTP submission service.
Spanish National Cancer Research Center (CNIO) — Research Technician
May 2016 – Jun 2017Madrid, Spain
Spain's national cancer research institute, focused on molecular oncology.
- Developed a reproducible workflow to identify mutation clusters in protein structures, including web-based visualization.
- Contributed to the European OpenMinTeD NLP/text-mining project, developing services and APIs for biomedical text analysis.
Education
Master in Master in Bioinformatics and Computational Biology
Sep 2015 – May 2016Instituto de Salud Carlos III
Master's Thesis: Structure-PPi v2.0: Module for Annotating Cancer-Related Single-Nucleotide Variants at Protein-Protein Interfaces.
Bachelor in Computer Engineering (Information Technologies)
Oct 2011 – Sep 2015Universidad Complutense de Madrid
Bachelor's Thesis: Computer Vision Adapted to Optical Coherence Tomographies.
Certifications
Teaching
NLP & Text Mining for Bioinformatics
Apr 2017 – May 2017Guest Lecturer · Instituto de Salud Carlos III
Designed and delivered a 15-hour intensive module on biomedical text mining and NLP for the Master in Bioinformatics and Computational Biology (Madrid).
- Large-scale literature extraction from PubMed and PMC via the NCBI Entrez API (BioPython, ESearch, EFetch).
- NLP pipelines in Python/NLTK: tokenization, POS tagging, n-grams, inverted indexing, lemmatization, and stemming — adapted for bioinformaticians with varied programming backgrounds.