Publications on Miguel Madrid-Mencíahttps://mimame.dev/publications/Recent content in Publications on Miguel Madrid-MencíaHugo -- gohugo.ioen© 2026 Miguel Madrid-MencíaThu, 11 Apr 2024 00:00:00 +0000Machine learning pipeline for genome-wide association studieshttps://mimame.dev/publications/patent-gwas-ml/Thu, 11 Apr 2024 00:00:00 +0000https://mimame.dev/publications/patent-gwas-ml/A machine learning approach to predict causal genes from GWAS summary statistics, substantially improving identification precision and recall. Assignee: Illumina Inc.Cytidine deaminase resolves replicative stress and protects pancreatic cancer from DNA-targeting drugshttps://mimame.dev/publications/cda-pancreatic-cancer/Mon, 01 Apr 2024 00:00:00 +0000https://mimame.dev/publications/cda-pancreatic-cancer/CDA overexpression in pancreatic adenocarcinoma resolves replicative stress at forks and correlates with resistance to DNA-damaging chemotherapy.STAG2 loss-of-function affects short-range genomic contacts and modulates the basal-luminal transcriptional program of bladder cancer cellshttps://mimame.dev/publications/stag2-bladder-cancer/Mon, 08 Nov 2021 00:00:00 +0000https://mimame.dev/publications/stag2-bladder-cancer/STAG2 loss-of-function links cohesin variant distribution to a basal transcriptional shift in bladder cancer, offering new insights into tumor suppressor mechanisms.Low replicative stress triggers cell-type specific inheritable advanced replication timinghttps://mimame.dev/publications/replication-timing/Fri, 07 May 2021 00:00:00 +0000https://mimame.dev/publications/replication-timing/Low replicative stress induces inheritable advances in replication timing at specific chromosomal domains, with potential impacts on cellular identity and gene expression.Insights on TAM formation from a Boolean model of macrophage polarization based on in vitro studieshttps://mimame.dev/publications/tam-boolean-model/Mon, 07 Dec 2020 00:00:00 +0000https://mimame.dev/publications/tam-boolean-model/A Boolean model of macrophage polarization extended to tumor microenvironment conditions, predicting potential regulators such as STAT1 and EGF as immunotherapy targets.Single-Cell Virtual Cytometer allows user-friendly and versatile analysis and visualization of multimodal single cell RNAseq datasetshttps://mimame.dev/publications/virtual-cytometer/Mon, 01 Jun 2020 00:00:00 +0000https://mimame.dev/publications/virtual-cytometer/Open-source software for flow cytometry-like visualization and exploration of pre-processed multi-omics single cell datasets.Using GARDEN-NET and ChAseR to explore human haematopoietic 3D chromatin interaction networkshttps://mimame.dev/publications/garden-net-chaser/Thu, 07 May 2020 00:00:00 +0000https://mimame.dev/publications/garden-net-chaser/First-author. An R package and web-based visualization tool for the representation, analysis, and integration of epigenomic data in the context of 3D chromatin interaction networks.DoriTool: a bioinformatics integrative tool for post-association functional annotationhttps://mimame.dev/publications/doritool/Tue, 19 Sep 2017 00:00:00 +0000https://mimame.dev/publications/doritool/An integrative bioinformatics pipeline for post-association functional annotation, combining data from multiple functional tools to maximize reproducibility and reduce researcher workload.